The NCR3 Polyclonal Antibody (CAB7153) is a valuable tool for researchers studying NCR3, a cell surface receptor involved in immune response regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot experiments. By targeting the NCR3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for investigations in the fields of immunology and oncology.NCR3, also known as Natural Cytotoxicity Triggering Receptor 3, plays a crucial role in the activation and regulation of natural killer cells, key players in the body's defense against infections and tumors.
Understanding the functions of NCR3 is essential for unraveling the complexities of immune responses in health and disease, making this antibody an indispensable resource for researchers studying conditions such as cancer, infectious diseases, and autoimmune disorders. By providing detailed insights into the role of NCR3, this antibody paves the way for the development of targeted therapies aimed at modulating immune responses for therapeutic benefit.
Product Name:
NCR3 Rabbit Polyclonal Antibody
SKU:
CAB7153
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-135 of human NCR3 (NP_667341.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
22kDa
Observed MW:
22kDa
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
259197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Daudi, using NCR3 Rabbit pAb (CAB7153) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
