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NCR3 Monoclonal Antibody [PAT38D9AT] (CPAB0696)

SKU:
CPAB0696
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT38D9AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

NCR3 Monoclonal Antibody [PAT38D9AT] (CPAB0696)

The NCR3 Polyclonal Antibody (CPAB0696) is a valuable tool for researchers studying the NCR3 protein, a cell surface receptor with important implications in immune function. The antibody is produced in rabbits and exhibits high reactivity with human samples, making it an ideal choice for Western blot applications. By binding specifically to NCR3, this antibody enables the accurate detection and analysis of NCR3 protein in various cell types, providing valuable insights for immunology and cancer research studies.

NCR3, also known as natural cytotoxicity triggering receptor 3, is a key player in the regulation of natural killer cell activity and immune responses. Its role in modulating immune function suggests its potential as a target for therapeutic interventions in diseases such as cancer, viral infections, and autoimmune disorders. By investigating the function of NCR3, researchers can uncover new opportunities for developing treatments that manipulate the immune system to combat these conditions effectively.

Product Name:NCR3 antibody
Product Sku:CPAB0696
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NCR3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NCR3 protein 19-138 amino acids purified from Ecoli.
Clone:PAT38D9AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:NCR3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Cytotoxicity Triggering Receptor 3 also known as NCR3 is a natural cytotoxicity receptor (NCR) which assists NK cells in the lysis of tumor cells. Moreover, NCR3 interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of NCR3 has been related with mild malaria suceptibility. Three transcript variants encoding various isoforms have been found for this gene.
Synonyms:Natural Cytotoxicity Triggering Receptor 3, LY117, 1C7, Lymphocyte Antigen 117, Activating Natural Killer Receptor P30, Natural Killer Cell P30-Related Protein, NK-p30, NKp30, CD337, MALS, Activating NK-A1 Receptor, CD337 Antigen, NKP30.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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