NCOR1 Rabbit Polyclonal Antibody (CAB7046)
- SKU:
- CAB7046
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NCOR1 Rabbit Polyclonal Antibody |
SKU: | CAB7046 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NCOR1 (NP_006302.2). |
Sequence: | MSSS GYPP NQGA FSTE QSRY PPHS VQYT FPNT RHQQ EFAV PDYR SSHL EVSQ ASQL LQQQ QQQQ LRRR PSLL SEFH PGSD RPQE RRTS YEPF HPGP SPVD HDSL ESKR PRLE QVSD SHFQ RVSA AVLP LVHP LPEG LRAS ADAK KDPA FGGK HEAP SSPI SGQP CGDD QNAS PSKL SKEE LIQS MDRV DREI AKVE QQIL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | N-CoR; TRAC1; N-CoR1; hN-CoR; PPP1R109; NCOR1 |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 270kDa |
Observed MW: | 270kDa |
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
Purification Method: | Affinity purification |
Gene ID: | 9611 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |