The NCMAP Antibody (PAC036642) is a polyclonal antibody designed for research involving NCMAP, a cell surface molecule with implications in neurodegenerative diseases such as Alzheimer's. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including immunofluorescence and flow cytometry. It specifically binds to the NCMAP protein, allowing for detection and analysis in different cell types, making it an ideal tool for studies in neuroscience and neurology research.
NCMAP, also known as neural cell adhesion molecule-associated protein, plays a crucial role in synaptic function and neuronal development. Dysregulation of NCMAP has been linked to neurodegenerative disorders, making it a promising target for research into Alzheimer's disease and other neurological conditions. Understanding the function of NCMAP is essential for developing potential therapies that target this protein and its associated pathways in the treatment of neurodegenerative diseases.
Immunofluorescent analysis of HepG2 cells using PACO36642 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human testis tissue using PACO36642 at dilution of 1:100.
Background:
Plays a role in myelin formation.
Synonyms:
Noncompact myelin-associated protein (Myelin protein of 11 kDa) (MP11), NCMAP, C1orf130
UniProt Protein Function:
NCMAP: Plays a role in myelin formation.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 1p36.11Cellular Component: integral to plasma membrane; paranode region of axonMolecular Function: structural constituent of myelin sheathBiological Process: myelin formation in the peripheral nervous system; positive regulation of myelination
