The NCLN Polyclonal Antibody (PAC010761) is a valuable tool for researchers studying the protein NCLN, which plays a critical role in cellular function and metabolism. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.NCLN is a key player in lipid metabolism and cellular homeostasis, making it an attractive target for research in metabolic disorders, cancer, and other related conditions. By utilizing this antibody, researchers can detect and analyze NCLN protein levels in various cell types, providing insight into its function and potential therapeutic implications.
With its high reactivity and specificity, the NCLN Polyclonal Antibody is an essential tool for studies in cell biology, metabolism, and disease research. By understanding the role of NCLN in cellular pathways, researchers can further our knowledge of disease mechanisms and potential treatment strategies.
NCLN: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Belongs to the nicastrin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: endoplasmic reticulum membrane; membrane; integral to membraneMolecular Function: protein bindingBiological Process: regulation of signal transduction