The NCKIPSD Polyclonal Antibody (PACO10759) is a valuable tool for researchers studying the NCKIPSD protein, a key player in cell signaling pathways involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NCKIPSD protein, researchers can effectively detect and analyze its expression in different cell types, making it an essential component in studies related to cell signaling, neurotransmission, and synaptic plasticity.
NCKIPSD, also known as NCK interacting protein with SH3 domain, is involved in mediating signal transduction events in neurons and plays a crucial role in synaptic function. Its function in regulating post-synaptic receptor trafficking and neurotransmitter release makes it a promising target for research into neurological disorders like Alzheimer's disease, Parkinson's disease, and schizophrenia. Understanding the role of NCKIPSD in these conditions can lead to the development of novel therapies aimed at restoring normal neuronal function and improving cognitive outcomes.
NCK interacting protein with SH3 domain;NCKIPSD;AF3P21;DIP;DIP1;MGC23891;ORF1;SPIN90;WASLBP;WISH ;
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NCBI Summary:
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
