The NCK2 Polyclonal Antibody (CAB7750) is a valuable tool for researchers studying NCK2, a key signaling protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications. By targeting the NCK2 protein, this antibody enables precise detection and analysis in a wide range of cell types, which is particularly useful for investigations in cell biology and cancer research.NCK2, also known as NCK adaptor protein 2, plays a crucial role in intracellular signaling pathways by mediating protein-protein interactions and regulating cytoskeletal dynamics.
Its involvement in cell migration, growth, and differentiation makes it a promising target for studying diseases such as cancer and neurological disorders. By understanding the function of NCK2, researchers can gain insights into the underlying mechanisms of these conditions and potentially develop new therapeutic strategies to target NCK2-related pathways.
Product Name:
NCK2 Rabbit Polyclonal Antibody
SKU:
CAB7750
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human NCK2 (NP_003572.2).
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
8440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NCK2 Rabbit pAb (CAB7750) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
