The NCK Rabbit Monoclonal Antibody (CAB9129) is a vital tool for researchers studying the NCK protein, a key player in cell signaling pathways and cytoskeletal dynamics. This antibody, produced in rabbits, is highly specific for detecting NCK in human samples and has been validated for use in Western blot applications.NCK is a crucial adapter protein that links cell surface receptors to downstream signaling molecules, playing a critical role in processes such as cell growth, differentiation, and migration. Its involvement in various cellular functions makes it a valuable target for research in various fields, including cancer biology, cell biology, and developmental biology.
By using the NCK Rabbit Monoclonal Antibody (CAB9129), researchers can accurately detect and analyze the expression of NCK in different cell types, aiding in the understanding of its function and interactions with other molecules. This antibody is essential for studies seeking to unravel the intricate signaling networks that drive cellular processes and contribute to disease pathogenesis.
Product Name:
NCK1 Rabbit Monoclonal Antibody
SKU:
CAB9129
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NCK11 (P16333).
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method:
Affinity purification
Gene ID:
4690
Clone Number:
ARC1441
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NCK11 Rabbit mAb (CAB9129) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
