The NCF1 Rabbit Monoclonal Antibody (CAB5143) is a valuable tool for researchers studying NCF1, a key component in the regulation of immune responses. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NCF1 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in the fields of immunology and cancer research.NCF1, also known as neutrophil cytosolic factor 1, plays a crucial role in the activation of immune cells and the production of reactive oxygen species. Its involvement in immune response modulation highlights its importance as a target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of NCF1 is essential for the development of therapeutic strategies that target or modulate immune activity in these disease contexts.Overall, the NCF1 Rabbit Monoclonal Antibody (CAB5143) offers researchers a highly specific and reliable tool for studying the role of NCF1 in immune regulation and disease pathogenesis. Its versatility and accuracy make it a valuable asset in advancing our understanding of immune responses and developing novel treatment approaches.
Product Name:
p47phox/NCF1 Rabbit Monoclonal Antibody
SKU:
CAB5143
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 291-390 of human p47phox/NCF1 (P14598).
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.
Purification Method:
Affinity purification
Gene ID:
653361
Clone Number:
ARC1206
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Raji cells, using p47phox/NCF1 Rabbit mAb (CAB5143) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
