The Ncaph Polyclonal Antibody (CAB4548) is a valuable tool for researchers studying Ncaph, a key protein involved in chromosome condensation and sister chromatid cohesion during cell division. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By specifically binding to the Ncaph protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in genetics, cell biology, and cancer research.
Ncaph is essential for proper chromosome segregation and maintenance of genomic stability, making it a crucial player in cell division and DNA replication processes. Dysregulation of Ncaph has been linked to chromosomal instability and tumorigenesis, highlighting its importance in cancer development and progression. By targeting Ncaph, researchers can gain valuable insights into the mechanisms underlying genetic disorders and cancer, potentially leading to the development of novel therapeutic strategies.
Product Name:
NCAPH Rabbit Polyclonal Antibody
SKU:
CAB4548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NCAPH (NP_056156.2).
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described.
Purification Method:
Affinity purification
Gene ID:
23397
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NCAPH antibody (CAB4548) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
