The NCAPG2 Antibody (PAC019385) is a polyclonal antibody designed for research involving NCAPG2, a protein involved in various cellular processes, such as cell division and DNA repair. This antibody, created through rabbit immunization, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the NCAPG2 protein, this antibody allows for the detection and analysis of NCAPG2 in different cell types, making it ideal for studies in molecular biology and cancer research.NCAPG2, also known as non-SMC condensin II complex subunit G2, plays a vital role in chromosome segregation during cell division and is essential for maintaining genomic stability.
Dysregulation of NCAPG2 has been implicated in cancer development and progression, highlighting its potential as a therapeutic target for cancer treatment. Research into the function and regulation of NCAPG2 is crucial for identifying new strategies to combat cancer and other diseases associated with genomic instability.Overall, the NCAPG2 Antibody offers a valuable tool for researchers investigating the role of NCAPG2 in cellular processes and disease pathology, paving the way for advancements in cancer therapy and personalized medicine.
Antibody Name:
NCAPG2 Antibody (PACO19385)
Antibody SKU:
PACO19385
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human NCAPG2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19385(NCAPG2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19385(NCAPG2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants.
Synonyms:
non-SMC condensin II complex, subunit G2
UniProt Protein Function:
LUZP5: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q36.3Cellular Component: membrane; nucleoplasmMolecular Function: methylated histone residue binding; protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
