The NCAPG Polyclonal Antibody (CAB13123) is a valuable tool for researchers studying NCAPG, a key protein involved in cell division and cell cycle regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to NCAPG, this antibody enables the detection and analysis of the protein in various cell types, making it an essential component for studies in genetics, cancer biology, and cell biology.NCAPG, or non-SMC condensin I complex subunit G, plays a crucial role in ensuring the accurate segregation of chromosomes during cell division.
Dysregulation of NCAPG has been implicated in various diseases, including cancer, where abnormal cell division leads to tumor formation and progression. By investigating the function and regulation of NCAPG, researchers can gain insights into the mechanisms driving these pathological processes and identify potential targets for therapeutic intervention.Overall, the NCAPG Polyclonal Antibody is a valuable tool for researchers seeking to unravel the complex mechanisms governing cell division and chromosome segregation, with implications for understanding and treating diseases such as cancer.
Product Name:
NCAPG Rabbit Polyclonal Antibody
SKU:
CAB13123
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 610-700 of human NCAPG (NP_071741.2).
This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64151
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NCAPG Rabbit pAb (CAB13123) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
