The NCAPD2 Polyclonal Antibody (CAB18412) is a valuable tool for researchers studying NCAPD2, a key protein involved in cell division and chromosome organization. This rabbit-derived antibody has high reactivity with human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of NCAPD2 in various cell types.NCAPD2, also known as non-SMC condensin I complex subunit D2, plays a crucial role in ensuring accurate chromosome segregation during cell division.
Dysregulation of NCAPD2 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. Understanding the function and regulation of NCAPD2 is essential for advancing research in oncology and cell biology.By utilizing the NCAPD2 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying cell division and chromosome dynamics, paving the way for new discoveries in cancer biology and potential therapeutic strategies.
Product Name:
NCAPD2 Rabbit Polyclonal Antibody
SKU:
CAB18412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1250-1350 of human NCAPD2 (NP_055680.3).
Enables histone binding activity. Involved in mitotic chromosome condensation. Located in condensed chromosome; cytosol; and nucleoplasm. Part of condensin complex. Colocalizes with cytoplasm and nuclear chromosome. Implicated in primary autosomal recessive microcephaly.
Purification Method:
Affinity purification
Gene ID:
9918
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NCAPD2 Rabbit pAb (CAB18412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
