The NBP Family Polyclonal Antibody (PACO01141) is a high-quality antibody designed for research involving the NBP family of proteins, including NBPF1, NBPF9, NBPF10, NBPF12, NBPF14, NBPF15, NBPF16, and NBPF20. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal tool for studying the function and expression of the NBP family of proteins.The NBP proteins have been implicated in various biological processes, including cell adhesion, signal transduction, and immune response regulation. The NBP Family Polyclonal Antibody can be used in Western blot applications to detect and analyze these proteins in different cell types, providing valuable insights into their roles in cell biology and disease pathology.
Research into the NBP family of proteins has the potential to uncover new therapeutic targets for conditions such as cancer, neurodevelopmental disorders, and immune-related diseases. By using the NBP Family Polyclonal Antibody, researchers can further explore the functions and mechanisms of action of these proteins, advancing our understanding of their involvement in human health and disease.
synthesized peptide derived from the C-terminal region of human NBPF1/9/10/12/14/15/16/20.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NBPF12; COAS1; KIAA1245; Neuroblastoma breakpoint family member 12; Chromosome 1 amplified sequence 1; NBPF10; Neuroblastoma breakpoint family member 10; NBPF16; Neuroblastoma breakpoint family member 16; NBPF1; KIAA1693; Neuroblastoma brea
UniProt Protein Function:
NBPF12: Belongs to the NBPF family.Chromosomal Location of Human Ortholog: 1q21Cellular Component: cytoplasm
UniProt Protein Details:
NCBI Summary:
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013]
