The NBEAL1 Polyclonal Antibody (PACO05073) is a crucial tool for researchers studying NBEAL1, a protein that plays a key role in vesicle trafficking and organelle dynamics within cells. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting NBEAL1 in human samples, making it an ideal choice for Western blot applications.NBEAL1 is involved in the regulation of melanosomes and platelet granules, making it a crucial component in various cellular processes. Dysregulation of NBEAL1 has been implicated in diseases such as Hermansky-Pudlak syndrome, a rare disorder characterized by albinism and bleeding disorders.
By studying NBEAL1 using this antibody, researchers can gain valuable insights into its function and potential implications in disease pathology.The NBEAL1 Polyclonal Antibody is a valuable tool for researchers in cell biology, genetics, and molecular biology seeking to elucidate the role of NBEAL1 in cellular processes and disease mechanisms. Its high specificity and sensitivity make it an essential component of any study involving NBEAL1 and its functions within the cell.
Antibody Name:
NBEAL1 Antibody (PACO05073)
Antibody SKU:
PACO05073
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human NBEAL1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NBEAL1; ALS2CR16; ALS2CR17; Neurobeachin-like protein 1; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein
UniProt Protein Function:
NBEAL1: Belongs to the WD repeat neurobeachin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q33.2Cellular Component: endomembrane system; extrinsic to membraneMolecular Function: phospholipid binding
