The NBAS Polyclonal Antibody (CAB4748) is a valuable tool for researchers studying the Nicastrin Binding and Regulating SPP Antibody, a key player in the regulation of intracellular protein processing and trafficking. This polyclonal antibody is produced from rabbit serum, ensuring high reactivity and specificity for human samples. Validated for use in Western blot applications, this antibody specifically binds to the NBAS protein, allowing for accurate detection and analysis in a variety of cell types. Its versatility makes it an ideal choice for studies focusing on intracellular protein dynamics, membrane trafficking, and molecular interactions.
The NBAS protein is involved in multiple cellular processes, including endoplasmic reticulum (ER) function, Golgi organization, and vesicular transport. Dysregulation of NBAS has been linked to various diseases, making it a promising target for research in fields such as cell biology, neurobiology, and genetic disorders.By using the NBAS Polyclonal Antibody (CAB4748), researchers can gain valuable insights into the mechanisms underlying protein trafficking and organelle dynamics, leading to a better understanding of disease pathogenesis and potential therapeutic interventions.
Product Name:
NBAS Rabbit Polyclonal Antibody
SKU:
CAB4748
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NBAS (NP_056993.2).
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly.
Purification Method:
Affinity purification
Gene ID:
51594
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NBAS antibody (CAB4748) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
