The NAV1 Antibody (PACO05652) is a polyclonal antibody specifically designed for research involving the NAV1 protein. NAV1 is a cell surface molecule that plays a crucial role in immune regulation, particularly in inhibiting immune responses. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the NAV1 protein, this antibody enables researchers to detect and analyze NAV1 in various cell types. The NAV1 protein is known for its role in immune homeostasis, regulating inflammation and inhibiting allergic reactions.
Its significance in immune response modulation makes it a valuable target for research in areas such as immunology and cancer. Understanding the activity of NAV1 is crucial for developing therapies that can modulate immune function in diseases like cancer, autoimmune disorders, and chronic inflammatory conditions. Overall, the NAV1 Antibody (PACO05652) is a valuable tool for researchers studying immune regulation and its implications in various disease states.
Antibody Name:
NAV1 Antibody (PACO05652)
Antibody SKU:
PACO05652
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:40000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human Neuron Navigator 1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
NAV1: May be involved in neuronal migration. Belongs to the Nav/unc-53 family. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; CytoskeletalChromosomal Location of Human Ortholog: 1q32.3Cellular Component: cytoplasm; microtubuleMolecular Function: protein bindingBiological Process: microtubule bundle formation; neuron migration
UniProt Protein Details:
NCBI Summary:
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
