The NAT8 Polyclonal Antibody (CAB7759) is specifically designed for research involving NAT8, a protein involved in various cellular processes such as neurotransmitter metabolism and kidney function. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. NAT8, also known as N-acetyltransferase 8, has been implicated in conditions such as neurodegenerative diseases, kidney disorders, and metabolic syndromes. Research into the function and regulation of NAT8 is crucial for understanding its role in these conditions and developing potential therapies.
The NAT8 Polyclonal Antibody enables detection and analysis of NAT8 protein in a variety of cell types, making it an ideal tool for researchers in fields such as neuroscience, nephrology, and metabolism. By studying the expression and activity of NAT8, scientists can gain valuable insights into its functions and potential therapeutic targets.
Product Name:
NAT8 Rabbit Polyclonal Antibody
SKU:
CAB7759
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 61-220 of human NAT8 (Q9UHE5).
Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Single-pass type II membrane protein.
Calculated MW:
26kDa
Observed MW:
26kDa
This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene.
Purification Method:
Affinity purification
Gene ID:
9027
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NAT8 Rabbit pAb (CAB7759) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
