The NAT1 Polyclonal Antibody (CAB1563) is a crucial tool for researchers studying NAT1, a gene involved in drug metabolism and detoxification processes in the body. The antibody, produced in rabbit host species, shows high specificity for human samples and is validated for use in various applications, including Western blotting.N-acetyltransferase 1 (NAT1) is known for its role in the metabolism of a wide range of drugs, carcinogens, and environmental toxins. Variations in NAT1 expression and activity have been linked to drug toxicity, cancer susceptibility, and other health conditions.
This antibody recognizes the NAT1 protein, allowing for precise detection and quantification in different cell types and tissues.By using the NAT1 Polyclonal Antibody, researchers can explore the function and regulation of NAT1 in various physiological and pathological processes. Understanding the activity of NAT1 is essential for developing personalized medicine approaches and improving drug safety and efficacy in clinical settings.
Product Name:
NAT1 Rabbit Polyclonal Antibody
SKU:
CAB1563
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human NAT1 (NP_001153646.1).
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of U-937 cells, using NAT1 antibody (CAB1563) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
