The NASP Polyclonal Antibody (CAB6938) is a powerful tool for researchers studying NASP, a protein involved in chromatin assembly. This antibody, raised in rabbits, is highly specific and reacts with NASP from various species, including human, mouse, and rat samples. Validated for use in immunofluorescence and immunoprecipitation assays, this antibody allows for the detection and analysis of NASP in a variety of cell types.NASP plays a crucial role in facilitating the assembly of nucleosomes, which are the building blocks of chromatin. By studying NASP, researchers can gain insights into the regulation of gene expression, DNA replication, and DNA repair processes.
Its involvement in these fundamental cellular mechanisms makes NASP a key target for research in the fields of molecular biology, genetics, and cancer biology.With its high specificity and versatility in various experimental techniques, the NASP Polyclonal Antibody (CAB6938) is an essential tool for researchers investigating the functions and regulatory mechanisms of NASP in both normal and disease states. Unlocking the mysteries of NASP could lead to advancements in understanding chromatin biology and developing novel therapeutic strategies for diseases associated with aberrant chromatin structure and function.
Product Name:
NASP Rabbit Polyclonal Antibody
SKU:
CAB6938
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-449 of human NASP (NP_689511.2).
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
Purification Method:
Affinity purification
Gene ID:
4678
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NASP Rabbit pAb (CAB6938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
