NARS2 Antibody (PACO10735)
- SKU:
- PACO10735
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
NARS2 Antibody (PACO10735)
The NARS2 Polyclonal Antibody (PACO10735) is specifically designed for research involving the NARS2 protein, which is essential for mitochondrial function and protein synthesis. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the NARS2 protein, this antibody allows for the detection and analysis of NARS2 in various cell types, making it an ideal tool for studies in mitochondrial biology and related diseases.
NARS2 is a key player in mitochondrial tRNA metabolism, linking it to the overall function of the mitochondria and cellular energy production. Dysregulation of NARS2 has been implicated in mitochondrial diseases and neurological disorders, making it a valuable target for research in these areas. Understanding the role of NARS2 can provide insights into the molecular mechanisms underlying these conditions and potentially lead to the development of novel therapeutic strategies.
| Antibody Name: | NARS2 Antibody (PACO10735) |
| Antibody SKU: | PACO10735 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human NARS2 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | asparaginyl-tRNA synthetase 2, mitochondrial (putative);NARS2;FLJ23441;SLM5 ; |
| UniProt Protein Function: | NARS2: Belongs to the class-II aminoacyl-tRNA synthetase family. |
| UniProt Protein Details: | Protein type:Ligase; EC 6.1.1.22; Translation; Mitochondrial Chromosomal Location of Human Ortholog: 11q14.1 Cellular Component: mitochondrion Molecular Function:asparagine-tRNA ligase activity Biological Process: asparaginyl-tRNA aminoacylation Disease: Combined Oxidative Phosphorylation Deficiency 24 |
| NCBI Summary: | This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015] |
| UniProt Code: | Q96I59 |
| NCBI GenInfo Identifier: | 296452944 |
| NCBI Gene ID: | 79731 |
| NCBI Accession: | Q96I59.3 |
| UniProt Secondary Accession: | Q96I59,G3V178, |
| UniProt Related Accession: | Q96I59 |
| Molecular Weight: | 28,783 Da |
| NCBI Full Name: | Probable asparagine--tRNA ligase, mitochondrial |
| NCBI Synonym Full Names: | asparaginyl-tRNA synthetase 2, mitochondrial (putative) |
| NCBI Official Symbol: | NARS2Â Â |
| NCBI Official Synonym Symbols: | SLM5; asnRS; DFNB94Â Â |
| NCBI Protein Information: | probable asparagine--tRNA ligase, mitochondrial |
| UniProt Protein Name: | Probable asparagine--tRNA ligase, mitochondrial |
| UniProt Synonym Protein Names: | Asparaginyl-tRNA synthetase; AsnRS |
| UniProt Gene Name: | NARS2Â Â |
| UniProt Entry Name: | SYNM_HUMAN |
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