The NAPB Polyclonal Antibody (CAB18223) is a valuable tool for researchers studying NAPB, a protein involved in synaptic transmission and neuronal signaling. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to NAPB, it enables the detection and analysis of this important protein in various cell types, making it ideal for studies in neuroscience and neurology.NAPB, also known as SNAP receptor, plays a crucial role in the release of neurotransmitters and the communication between neurons in the brain. Dysregulation of NAPB has been implicated in various neurological disorders, including epilepsy, Alzheimer's disease, and Parkinson's disease.
Research into the function of NAPB is essential for developing a better understanding of these conditions and exploring potential therapeutic interventions targeting synaptic dysfunction.Overall, the NAPB Polyclonal Antibody (CAB18223) is a reliable reagent for investigating the role of NAPB in neuronal communication and its implications for neurological health and disease. By using this antibody, researchers can further our understanding of synaptic transmission and potentially uncover new insights into the mechanisms underlying neurological disorders.
Product Name:
NAPB Rabbit Polyclonal Antibody
SKU:
CAB18223
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-50 of human NAPB (NP_071363.1).
This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain tissue. The encoded protein also interacts with the GluR2 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminus and may play a role as a chaperone in the molecular processing of the AMPA receptor.
Purification Method:
Affinity purification
Gene ID:
63908
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NAPB Rabbit pAb (CAB18223) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
