NANS Rabbit Polyclonal Antibody (CAB4778)
- SKU:
- CAB4778
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NANS
- HEL-S-100
- SAS
- SEMDCG
- SEMDG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NANS Rabbit Polyclonal Antibody |
SKU: | CAB4778 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-359 of human NANS (NP_061819.2). |
Sequence: | AELV RSVR LVER ALGS PTKQ LLPC EMAC NEKL GKSV VAKV KIPE GTIL TMDM LTVK VGEP KGYP PEDI FNLV GKKV LVTV EEDD TIME ELVD NHGK KIKS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SAS; SEMDG; SEMDCG; HEL-S-100; NANS |
Positive Sample: | A-549,OVCAR3,A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Purification Method: | Affinity purification |
Gene ID: | 54187 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |