The NanogP8 Monoclonal Antibody (PACO36958) is a powerful tool for research involving the NanogP8 protein, a key player in stem cell pluripotency and cancer progression. This antibody, produced using advanced monoclonal antibody technology, exhibits high specificity and sensitivity for detecting NanogP8 in a variety of samples, making it an ideal choice for experiments such as immunofluorescence and flow cytometry.NanogP8 is a member of the Nanog family of transcription factors that play a critical role in maintaining the pluripotency of embryonic stem cells. Additionally, NanogP8 has been implicated in promoting tumor growth and metastasis in various types of cancer.
By targeting NanogP8 with this antibody, researchers can gain valuable insights into the mechanisms underlying these processes, potentially leading to the development of novel cancer therapies.Overall, the NanogP8 Monoclonal Antibody (PACO36958) offers researchers a reliable tool for studying the role of NanogP8 in stem cell biology and cancer research, furthering our understanding of these complex biological processes and ultimately contributing to the development of new treatments for cancer.
Antibody Name:
NANOGP8 Antibody (PACO36958)
Antibody SKU:
PACO36958
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Homeobox protein NANOGP8 protein (1-305AA)
Western Blot. Positive WB detected in: Rat liver tissue, Mouse liver tissue. All lanes: NANOGP8 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35 kDa. Observed band size: 35 kDa.
Background:
May act as a transcription regulator. When overexpressed, promotes entry of cells into S phase and cell proliferation.
Synonyms:
Homeobox protein NANOGP8, NANOGP8
UniProt Protein Function:
May act as a transcription regulator (). When overexpressed, promotes entry of cells into S phase and cell proliferation.
UniProt Protein Details:
NCBI Summary:
This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009]
