The Nanogp8 Polyclonal Antibody (PAC001136) is a vital tool for researchers studying the Nanogp8 protein, which is involved in stem cell pluripotency and self-renewal. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it an excellent choice for Western blot applications. By binding specifically to the Nanogp8 protein, this antibody allows for easy detection and analysis in a variety of cell types, making it an invaluable tool for studies in stem cell biology and regenerative medicine.Nanogp8 is a key player in maintaining the pluripotent state of stem cells, making it a crucial target for research aimed at understanding and harnessing the potential of stem cells for therapeutic purposes.
By studying the function and regulation of Nanogp8, researchers can gain valuable insights into the mechanisms that control stem cell fate and differentiation, paving the way for the development of novel stem cell-based therapies for a range of diseases and conditions.Overall, the Nanogp8 Polyclonal Antibody is a valuable asset for researchers interested in exploring the role of Nanogp8 in stem cell biology and regenerative medicine. Its high reactivity, specificity, and reliability make it an essential tool for unraveling the complex mechanisms that govern stem cell pluripotency and differentiation.
Antibody Name:
NANOGP8 Antibody
Antibody SKU:
PACO01136
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Nanog P8.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NANOGP8; Putative homeobox protein NANOGP8
UniProt Protein Function:
May act as a transcription regulator (). When overexpressed, promotes entry of cells into S phase and cell proliferation.
UniProt Protein Details:
NCBI Summary:
This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009]
