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NANOG Monoclonal Antibody [P5A10AT] (CPAB0556)

SKU:
CPAB0556
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
P5A10AT
Applications:
WB
ELISA
IHC
€149
Frequently bought together:

Description

system_update_alt Datasheet

NANOG Monoclonal Antibody [P5A10AT] (CPAB0556)

Similarly, the Nanog Antibody (CPAB0556) offered by Assaygenie is a valuable tool for researchers studying the Nanog protein, a key transcription factor involved in maintaining pluripotency and self-renewal of embryonic stem cells. This polyclonal antibody, also raised in rabbits, exhibits high reactivity with human samples, making it suitable for a wide range of applications.Validated for use in Western blot, immunohistochemistry, and immunofluorescence, the Nanog Antibody binds specifically to the Nanog protein, allowing for precise detection and analysis in various experimental settings.

Its versatility and reliability make it an ideal choice for investigations into stem cell biology, developmental biology, and cancer research.Given the critical role of Nanog in regulating cell fate and differentiation, understanding its function is key to advancing regenerative medicine and cancer therapy. The Nanog Antibody from Assaygenie provides researchers with a powerful tool to explore the mechanisms underlying pluripotency and cellular reprogramming, paving the way for future breakthroughs in stem cell research and therapeutic applications.

Product Name:NANOG Antibody
Product Sku:CPAB0556
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NANOG mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NANOG amino acids 1-154 purified from Ecoli.
Clone:P5A10AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:NANOG antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Synonyms:NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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