UniProt Protein Function: | VGCNL1: a putative voltage-gated ion channelProtein type: Membrane protein, multi-pass; Channel, calcium; Membrane protein, integral; Transporter, ion channelChromosomal Location of Human Ortholog: 13q32.3Cellular Component: plasma membrane; integral to membraneMolecular Function: voltage-gated calcium channel activity; protein binding; sodium channel activityBiological Process: sperm motility; transmembrane transportDisease: Congenital Contractures Of The Limbs And Face, Hypotonia, And Developmental Delay; Hypotonia, Infantile, With Psychomotor Retardation And Characteristic Facies |
UniProt Protein Details: | |
NCBI Summary: | NALCN forms a voltage-independent, nonselective, noninactivating cation channel permeable to Na+, K+, and Ca(2+). It is responsible for the neuronal background sodium leak conductance (Lu et al., 2007 [PubMed 17448995]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8IZF0 |
NCBI GenInfo Identifier: | 24119274 |
NCBI Gene ID: | 259232 |
NCBI Accession: | NP_443099.1 |
UniProt Secondary Accession: | Q8IZF0,Q6P2S6, Q6ZMI7, Q8IZZ1, Q8TAH1 |
UniProt Related Accession: | Q8IZF0 |
Molecular Weight: | 25,365 Da |
NCBI Full Name: | sodium leak channel non-selective protein |
NCBI Synonym Full Names: | sodium leak channel, non selective |
NCBI Official Symbol: | NALCNÂ Â |
NCBI Official Synonym Symbols: | IHPRF; INNFD; CanIon; VGCNL1; CLIFAHDD; bA430M15.1Â Â |
NCBI Protein Information: | sodium leak channel non-selective protein |
UniProt Protein Name: | Sodium leak channel non-selective protein |
UniProt Synonym Protein Names: | CanIon; Voltage gated channel-like protein 1 |
Protein Family: | Sodium leak channel non-selective protein |
UniProt Gene Name: | NALCNÂ Â |
UniProt Entry Name: | NALCN_HUMAN |