TBK1/NAK Rabbit Monoclonal Antibody (CAB3458)
- SKU:
- CAB3458
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TBK1/NAK Rabbit Monoclonal Antibody |
SKU: | CAB3458 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TBK1/NAK (Q9UHD2). |
Sequence: | MQST SNHL WLLS DILG QGAT ANVF RGRH KKTG DLFA IKVF NNIS FLRP VDVQ MREF EVLK KLNH KNIV KLFA IEEE TTTR HKVL IMEF CPCG SLYT VLEE |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | NAK; T2K; IIAE8; FTDALS4; TBK1/NAK |
Positive Sample: | 293T,Hep G2,Mouse lung,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 84kDa |
Observed MW: | 84kDa |
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response.
Purification Method: | Affinity purification |
Gene ID: | 29110 |
Clone Number: | ARC0778 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |