NAIP Rabbit Polyclonal Antibody (CAB16924)
- SKU:
- CAB16924
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | NAIP Rabbit Polyclonal Antibody |
SKU: | CAB16924 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 750-850 of human NAIP (NP_075043.1). |
Sequence: | LLRS IHFP IRGN KTSP RAHF SVLE TCFD KSQV PTID QDYA SAFE PMNE WERN LAEK EDNV KSYM DMQR RASP DLST GYWK LSPK QYKI PCLE VDVN DIDV V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BIRC1; NLRB1; psiNAIP; NAIP |
Positive Sample: | Rat spleen,Rat lung |
Cellular Localization: | basolateral plasma membrane, cytoplasm, inflammasome complex, IPAF inflammasome complex |
Calculated MW: | 160kDa |
Observed MW: | 160kDa |
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4671 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |