The NADPH Oxidase 5 Polyclonal Antibody (CAB7136) is a valuable tool for researchers studying NADPH oxidase 5, an enzyme complex involved in the production of reactive oxygen species (ROS) in immune cells. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications.NADPH oxidase 5 plays a crucial role in the immune system by generating ROS to help kill pathogens like bacteria and fungi. Dysregulation of this enzyme has been implicated in various inflammatory conditions and autoimmune diseases. The NADPH Oxidase 5 Polyclonal Antibody enables researchers to detect and quantify levels of NADPH oxidase 5 in different cell types, providing insights into its role in immune function and disease pathology.
By understanding the activity of NADPH oxidase 5, researchers can potentially develop novel therapeutic strategies for targeting ROS production and immune system regulation in conditions such as chronic inflammation, autoimmune disorders, and cancer. This antibody is therefore a valuable tool for studies in immunology, oncology, and inflammatory diseases.
Product Name:
NOX5 Rabbit Polyclonal Antibody
SKU:
CAB7136
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 661-765 of human NOX5 (NP_078781.3).
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
79400
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of PC-3 cells, using NOX5 antibody (CAB7136) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
