The NADPH Oxidase 1 Polyclonal Antibody (CAB8527) is a valuable tool for researchers studying the NADPH oxidase 1 enzyme, which plays a crucial role in the generation of reactive oxygen species (ROS) in immune cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.NADPH oxidase 1 is a key player in the immune response, functioning to produce ROS that are essential for killing pathogens and regulating immune signaling pathways. Dysregulation of NADPH oxidase 1 activity has been implicated in various diseases, including inflammatory disorders and cancer.
By specifically targeting NADPH oxidase 1, researchers can gain insights into the mechanisms underlying oxidative stress and inflammation, as well as explore potential therapeutic interventions for diseases associated with aberrant ROS production. The NADPH Oxidase 1 Polyclonal Antibody is a valuable tool for investigating the role of this enzyme in health and disease, making it a valuable asset for studies in immunology and cancer research.
Product Name:
NOX1 Rabbit Polyclonal Antibody
SKU:
CAB8527
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 415-564 of human NOX1 (NP_008983.2).
This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
27035
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NOX1 antibody (CAB8527) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
