The NADPH Oxidase 1 Polyclonal Antibody (CAB11966) is a versatile tool for researchers studying the NADPH oxidase 1 enzyme, which plays a crucial role in the production of reactive oxygen species (ROS) in phagocytic cells. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.NADPH oxidase 1 is a key player in the immune response, as it is responsible for generating ROS to help eliminate invading pathogens. Dysregulation of NADPH oxidase 1 has been implicated in various diseases, including inflammatory conditions and cancer.
By using this antibody to detect and analyze NADPH oxidase 1 expression, researchers can gain valuable insights into the role of this enzyme in these pathological processes.With its ability to bind specifically to NADPH oxidase 1, this antibody is an invaluable tool for studies in immunology, oncology, and inflammation. Understanding the function of NADPH oxidase 1 and its dysregulation in disease settings is essential for the development of targeted therapies to modulate ROS production and immune responses.
Product Name:
NOX1 Rabbit Polyclonal Antibody
SKU:
CAB11966
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 418-564 of human NOX1 (NP_008983.2?).
This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
27035
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using NOX1 Rabbit pAb (CAB11966) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
