The NACAD Antibody (PACO02754) is a critical tool for researchers studying NACAD, a protein involved in various cellular processes, including cell adhesion and migration. This polyclonal antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.NACAD plays a crucial role in cell-cell interactions and has been implicated in diseases such as cancer and developmental disorders. By binding to the NACAD protein, this antibody allows for the detection and analysis of NACAD in different cell types, making it an essential reagent for studies in cell biology and disease mechanisms.
Understanding the function and regulation of NACAD is essential for uncovering its role in disease pathology and identifying potential therapeutic targets. The NACAD Antibody provides researchers with a valuable tool to further investigate the biological functions of NACAD and its involvement in various disease states.
Antibody Name:
NACAD Antibody
Antibody SKU:
PACO02754
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human NACAD.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NACAD; KIAA0363; NAC-alpha domain-containing protein 1
UniProt Protein Function:
NACAD: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). Belongs to the NAC-alpha family.Chromosomal Location of Human Ortholog: 7p13Cellular Component: cytoplasm; nucleusBiological Process: protein transport
