NACA Monoclonal Antibody (CAB22165)
- SKU:
- CAB22165
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | NACA Monoclonal Antibody |
| SKU: | CAB22165 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human NACA (NP_005585.1). |
| Sequence: | MPGE ATET VPAT EQEL PQPQ AETG SGTE SDSD ESVP ELEE QDST QATT QQAQ LAAA AEID EEPV SKAK QSRS EKKA RKAM SKLG LRQV TGVT RVTI RKSK NILF VITK PDVY KSPA SDTY IVFG EAKI EDLS QQAQ LAAA EKFK VQGE AVSN IQEN TQTP TVQE ESEE EEVD ETGV EVKD IELV MSQA NVSR AKAV RALK NNSN DIVN AIME LTM |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:2000 - 1:20000 |
| Synonyms: | HSD48; NACA1; skNAC; NAC-alpha; NACA |
| Positive Sample: | 293F,Daudi,RAW264.7,Rat thymus,Rat spleen |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 23kDa |
| Observed MW: | 37kDa |
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
| Purification Method: | Affinity purification |
| Gene ID: | 4666 |
| Clone Number: | ARC53721 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates, using NACA antibody (CAB22165) at1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s. |
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