NAB2 Rabbit Polyclonal Antibody (CAB5827)
- SKU:
- CAB5827
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NAB2 Rabbit Polyclonal Antibody |
SKU: | CAB5827 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NAB2 (NP_005958.1). |
Sequence: | MHRA PSPT AEQP PGGG DSAR RTLQ PRLK PSAR AMAL PRTL GELQ LYRV LQRA NLLS YYET FIQQ GGDD VQQL CEAG EEEF LEIM ALVG MATK PLHV RRLQ KALR EWAT NPGL FSQP VPAV PVSS IPLF KISE TAGT RKGS MSNG HGSP GEKA GSAR SFSP KSPL ELGE KLSP LPGG PGAG DPRI WPGR STPE SDVG AGGE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MADER; NAB2 |
Positive Sample: | M21,Mouse lung,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 57kDa |
Observed MW: | 70kDa |
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 4665 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |