| UniProt Protein Function: | Function: May be catalytically inactive.Subcellular location: Membrane; Single-pass type II membrane protein Potential. Tissue specificity: Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.Miscellaneous: The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, Ref.1 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.Sequence similarities: Belongs to the peptidase M28 family. M28B subfamily.Caution: Although related to the peptidase M28 family, it lacks the conserved zinc-binding and active sites and therefore has probably lost hydrolase activity.Sequence caution: The sequence CAE54974.2 differs from that shown. Reason: Contaminating sequence at the C-terminus.The sequence CAH56310.1 differs from that shown. Reason: Frameshift at positions 509 and 518. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q58DX5 |
| NCBI GenInfo Identifier: | 34785667 |
| NCBI Gene ID: | 254827 |
| NCBI Accession: | AAH57243.1 |
| UniProt Secondary Accession: | Q58DX5 |
| UniProt Related Accession: | Q58DX5 |
| Molecular Weight: | |
| NCBI Full Name: | NAALADL2 protein |
| NCBI Synonym Full Names: | N-acetylated alpha-linked acidic dipeptidase like 2 |
| NCBI Official Symbol: | NAALADL2Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 |
| UniProt Protein Name: | Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | NAALADL2Â Â |
| UniProt Entry Name: | NADL2_HUMAN |
