The NAA60 Polyclonal Antibody (CAB7386) is a powerful tool for researchers studying N-alpha-acetyltransferase 60 (NAA60), an enzyme involved in protein acetylation and regulation of cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NAA60 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for investigations in cell biology and cancer research.
NAA60 plays a crucial role in protein modification and cellular function, making it a key target for studying processes such as cell proliferation, apoptosis, and DNA repair. Understanding the function of NAA60 is essential for unraveling its implications in various diseases, including cancer and neurological disorders. By investigating the role of NAA60, researchers have the potential to uncover novel therapeutic approaches that target protein acetylation pathways for the treatment of these conditions.
Product Name:
NAA60 Rabbit Polyclonal Antibody
SKU:
CAB7386
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human NAA60 (NP_001077070.1).
This gene encodes an enzyme that localizes to the Golgi apparatus, where it transfers an acetyl group to the N-terminus of free proteins. This enzyme acts on histones, and its activity is important for chromatin assembly and chromosome integrity. Alternative splicing and the use of alternative promoters results in multiple transcript variants. The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting; transcript variants originating from this position are expressed from the maternal allele.
Purification Method:
Affinity purification
Gene ID:
79903
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293F cells, using NAA60 Rabbit pAb (CAB7386) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
