Anti-NAA40 Antibody (CAB7385)
- SKU:
- CAB7385
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Anti-NAA40 Antibody (CAB7385)
The NAA40 Polyclonal Antibody (CAB7385) is a valuable tool for researchers studying NAA40, a protein involved in N-terminal acetylation of proteins. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to NAA40, this antibody enables accurate detection and analysis of the protein in various cell types, making it ideal for studies in protein acetylation and post-translational modifications.NAA40 is essential for the acetylation of proteins at their N-termini, a process that plays a critical role in protein stability, localization, and function.
Dysregulation of N-terminal acetylation has been implicated in various diseases, including cancer and neurodegenerative disorders, making NAA40 a promising target for therapeutic interventions. By using the NAA40 Polyclonal Antibody, researchers can gain insights into the function and regulation of NAA40, paving the way for novel treatments and drug development in the future.
Antibody Name: | Anti-NAA40 Antibody |
Antibody SKU: | CAB7385 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human NAA40 (NP_079047.2). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human NAA40 (NP_079047.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MGRK SSKA KEKK QKRL EERA AMDA VCAK VDAA NRLG DPLE AFPV FKKY DRNG LNVS IECK RVSG LEPA TVDW AFDL TKTN MQTM YEQS EWGW KDRE KREE MTDD RAWY LIAW ENSS VPVA FSHF RFDV ECGD EVLY CYEV QLES KVRR KGLG KFLI QILQ LMAN STQM KKVM LTVF KHNH GAYQ FFRE ALQF EIDD SSPS MSGC CGED CSYE ILSR RTKF GDSH HSHA GGHC GGCC H |
Gene ID: | 79829 |
Uniprot: | Q86UY6 |
Cellular Location: | |
Calculated MW: | 22kDa/24kDa/27kDa |
Observed MW: | Refer to figures |
Synonyms: | NAA40, NAT11, NatD, PATT1, hNatD |
Background: |
UniProt Protein Function: | NAA40: Responsible for the acetylation of the N-terminal residues of histones H4 and H2A. Belongs to the acetyltransferase family. GNAT subfamily. |
UniProt Protein Details: | Protein type:Acetyltransferase; EC 2.3.1.- Chromosomal Location of Human Ortholog: 11q13.1 Molecular Function:N-acetyltransferase activity Biological Process: lipid metabolic process |
UniProt Code: | Q86UY6 |
NCBI GenInfo Identifier: | 74727506 |
NCBI Gene ID: | 79829 |
NCBI Accession: | Q86UY6.1 |
UniProt Secondary Accession: | Q86UY6,Q5HYL5, Q9H897, B4DR03, B4DU10, |
UniProt Related Accession: | Q86UY6 |
Molecular Weight: | 237 |
NCBI Full Name: | N-alpha-acetyltransferase 40 |
NCBI Synonym Full Names: | N(alpha)-acetyltransferase 40, NatD catalytic subunit |
NCBI Official Symbol: | NAA40Â Â |
NCBI Official Synonym Symbols: | NAT11; PATT1Â Â |
NCBI Protein Information: | N-alpha-acetyltransferase 40; natD catalytic subunit; N-alpha acetyl transferase 40; N-acetyltransferase 11 (GCN5-related, putative); N-alpha-acetyltransferase 40, NatD catalytic subunit; N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog |
UniProt Protein Name: | N-alpha-acetyltransferase 40 |
UniProt Synonym Protein Names: | N-acetyltransferase 11; NatD catalytic subunit |
Protein Family: | N-alpha-acetyltransferase |
UniProt Gene Name: | NAA40Â Â |
UniProt Entry Name: | NAA40_HUMAN |
Immunofluorescence analysis of A549 cells using NAA40 antibody (CAB7385). Blue: DAPI for nuclear staining. |