The NAA10 Polyclonal Antibody (CAB7009) is a valuable tool for researchers studying NAA10, a protein involved in a variety of cellular processes including protein acetylation and cell cycle regulation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the NAA10 protein, researchers can detect and analyze its expression in different cell types, making it an essential component of studies in molecular biology and cancer research.NAA10, also known as N-alpha-acetyltransferase 10, plays a crucial role in protein synthesis and turnover, making it an attractive target for investigating various diseases such as cancer and neurodegenerative disorders.
Understanding the function and regulation of NAA10 can provide insights into how disruptions in protein acetylation pathways contribute to disease progression. By using the NAA10 Polyclonal Antibody, researchers can further their understanding of NAA10's role in cellular physiology and potentially identify novel therapeutic targets for treating related conditions.
Product Name:
NAA10 Rabbit Polyclonal Antibody
SKU:
CAB7009
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 161-235 of human NAA10 (NP_003482.1).
Sequence:
HLEL KEKG RHVV LGAI ENKV ESKG NSPP SSGE ACRE EKGL AAED SGGD SKDL SEVS ETTE STDV KDSS EASD SAS
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8260
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NAA10 Rabbit pAb (CAB7009) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
