The Na+/K+ ATPase Rabbit Monoclonal Antibody is a valuable tool for researchers studying the Na+/K+ ATPase enzyme, a crucial membrane protein responsible for maintaining the electrochemical gradient across cell membranes. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for human samples, making it ideal for use in a variety of applications such as Western blotting and immunohistochemistry.The Na+/K+ ATPase enzyme is essential for various cellular functions, including maintaining cell volume, regulating membrane potential, and facilitating active transport of ions across cell membranes. Dysregulation of the Na+/K+ ATPase has been implicated in numerous diseases, including hypertension, heart failure, and neurological disorders.
By utilizing this antibody, researchers can accurately detect and analyze the expression of the Na+/K+ ATPase protein in different cell types, providing valuable insights into its role in health and disease.Overall, the Na+/K+ ATPase Rabbit Monoclonal Antibody is a reliable tool for studying the Na+/K+ ATPase enzyme and its implications in various biological processes. Its high specificity, sensitivity, and versatility make it an essential reagent for research in fields such as physiology, pharmacology, and neuroscience.
Product Name:
Na+/K+-ATPase Rabbit Monoclonal Antibody
SKU:
CAB11683
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Na+/K+-ATPase (P05023).
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
476
Clone Number:
ARC0674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using Na+/K+-ATPase Rabbit mAb (CAB11683) at 1:50000 dilution.Membrane protein extract isolated from Hela cells.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
