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Na /K -ATPase Polyclonal Antibody (CAB24883)

SKU:
CAB24883
$155
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Description

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Product Name:Na /K -ATPase Polyclonal Antibody
SKU:CAB24883
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 386-595 of human Na /K -ATPase（NP_000692.2）.
Sequence:MTVA HMWF DNQI HEAD TTEN QSGV SFDK TSAT WLAL SRIA GLCN RAVF QANQ ENLP ILKR AVAG DASE SALL KCIE LCCG SVKE MRER YAKI VEIP FNST NKYQ LSIH KNPN TSEP QHLL VMKG APER ILDR CSSI LLHG KEQP LDEE LKDA FQNA YLEL GGLG ERVL GFCH LFLP DEQF PEGF QFDT DDVN FPID NLCF VGLI SMID PP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:ATP1A1; ATPase Na+/K+ transporting subunit alpha 1; Na /K -ATPase
Positive Sample:C6
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Melanosome, Multi-pass membrane protein.
Calculated MW:74kDa/109kDa/112kDa/113kDa
Observed MW:100kDa

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:476/477/478/480
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from C6 cells using Na /K -ATPase Rabbit pAb(CAB24883) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.

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