The N6AMT1 Polyclonal Antibody (CAB7201) is a crucial tool for research involving N6AMT1, a key enzyme involved in the methylation of adenosine to regulate RNA modification. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it an ideal choice for experiments in which N6AMT1 expression and function need to be studied.N6AMT1 plays a vital role in epigenetic regulation and has been linked to various cellular processes, including gene expression and protein synthesis. By targeting N6AMT1, researchers can gain insights into the mechanisms underlying RNA methylation and its implications in biological functions.
The antibody is validated for use in Western blot applications, enabling accurate detection and analysis of N6AMT1 levels in different cell types, tissues, and experimental conditions.Understanding the role of N6AMT1 in RNA modification is essential for uncovering its potential involvement in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. With the N6AMT1 Polyclonal Antibody, researchers can delve deeper into the intricate mechanisms of RNA methylation and its impact on cellular processes, opening up new possibilities for therapeutic interventions and disease treatments.
Product Name:
N6AMT1 Rabbit Polyclonal Antibody
SKU:
CAB7201
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-186 of human N6AMT1/HEMK2 (NP_877426.3).
This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
Purification Method:
Affinity purification
Gene ID:
29104
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat kidney, using N6AMT1/HEMK2 Rabbit pAb (CAB7201) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
