null

N6-methyladenosine/m6A Rabbit Monoclonal Antibody (CAB19841)

SKU:
CAB19841
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

N6-methyladenosine/m6A Rabbit Monoclonal Antibody (CAB19841)

The N6-Methyladenosine (m6A) Rabbit Monoclonal Antibody (CAB19841) is a cutting-edge tool for researchers studying epigenetics and RNA modifications. This antibody is raised in rabbits and is highly specific for detecting m6A, a common RNA modification that plays a crucial role in regulating gene expression and protein translation.With validated use in various applications such as immunofluorescence and immunohistochemistry, this antibody allows for precise detection and analysis of m6A in different cell types and tissues. Its high reactivity with human samples makes it an ideal choice for studies in cancer, neurobiology, and developmental biology, where m6A has been implicated in various cellular processes.

The m6A Rabbit Monoclonal Antibody opens up new avenues for exploring the dynamic nature of RNA modifications and their impact on gene regulation. By targeting m6A, researchers can gain valuable insights into the complex mechanisms underlying disease development and progression, paving the way for novel therapeutic interventions and advancements in personalized medicine.

Product Name:N6-methyladenosine/m6A Rabbit Monoclonal Antibody
SKU:CAB19841
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Species independent
Immunogen:Chemical compounds corresponding to N6-methyladenosine / m6A.
Tested Applications:IF/ICC ELISA Nucleotide Array DB meRIP
Recommended Dilution:DB,1:500 - 1:2000 meRIP,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:N6-methyladenosine; m6A; N6-methyladenosine / m6A
Positive Sample:Arabidopsis

Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)

Purification Method:Protein A
Clone Number:ARC5003-10
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,0.05% BSA,50% glycerol,pH7.3.
Product ImageThe m6A rabbit monoclonal antibody (CAB19841) are tested in Dot Blot against N6-methyladenosine (m6A) and unmodified adenosine.Oligomer 8 - ATAACTGG-m6A-CCGAATGGOligomer 9 - ATAACTGGACCGAATGGOligomer 10 - AAAAAAAAAAAAAAAA-biotin.

Related Products