N-Myc/MYCN Monoclonal Antibody (CAB22175)
- SKU:
- CAB22175
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | N-Myc/MYCN Monoclonal Antibody |
SKU: | CAB22175 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human N-Myc/MYCN (NP_005369.2). |
Sequence: | MPSC STST MPGM ICKN PDLE FDSL QPCF YPDE DDFY FGGP DSTP PGED IWKK FELL PTPP LSPS RGFA EHSS EPPS WVTE MLLE NELW GSPA EEDA FGLG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | NMYC; ODED; MODED; N-myc; bHLHe37; MYCNsORF; MYCNsPEP; N-Myc/MYCN |
Positive Sample: | Neuro-2a |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 50kDa |
Observed MW: | 60kDa |
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4613 |
Clone Number: | ARC55217 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |