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N Antibody (PACO34226)

SKU:
PACO34226
Product Type:
Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339

Description

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N Antibody (PACO34226)

The N Antibody (PACO34226) is a highly specific and sensitive tool for studying the protein N, which is a key player in cellular pathways related to immune response and inflammation. This polyclonal antibody is produced using high-quality materials and has been extensively validated for use in various experimental applications, including Western blotting and immunofluorescence.The N protein is implicated in various cellular processes, including viral replication and host immune evasion, making it a valuable target for research in virology and immunology.

By using the N Antibody, researchers can gain insights into the mechanisms underlying viral pathogenesis and immune response modulation, providing opportunities for the development of novel antiviral therapies and vaccines.Overall, the N Antibody (PACO34226) is a versatile research tool that can significantly contribute to our understanding of viral infections, immune response pathways, and the development of targeted therapies for infectious diseases.

Antibody Name:N Antibody (PACO34226)
Antibody SKU:PACO34226
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Rabies virus
Immunogen:Recombinant Rabies virus Nucleoprotein protein (1-450AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Synonyms:Nucleoprotein (NP) (Nucleocapsid protein) (Protein N), N
UniProt Protein Function:Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:P15197
NCBI GenInfo Identifier:152031643
NCBI Gene ID:
NCBI Accession:P15197.2
UniProt Secondary Accession:P15197,Q4F903
UniProt Related Accession:P15197
Molecular Weight:50,748 Da
NCBI Full Name:Nucleoprotein
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:Nucleoprotein
UniProt Synonym Protein Names:Nucleocapsid protein; Protein N
Protein Family:
UniProt Gene Name:N  
UniProt Entry Name:NCAP_RABVA

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