The MYST1 Polyclonal Antibody (CAB2208) is a valuable tool for researchers interested in exploring the role of MYST1, a histone acetyltransferase enzyme involved in chromatin remodeling and gene transcription. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MYST1 protein, this antibody allows for the detection and analysis of MYST1 expression in various cell types, making it ideal for investigations in the fields of epigenetics and cancer research.
MYST1, a member of the MYST family of histone acetyltransferases, is known to play a crucial role in regulating gene expression through the modification of chromatin structure. Dysregulation of MYST1 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. By studying the function and regulation of MYST1, researchers can gain valuable insights into the mechanisms underlying disease development and progression, potentially paving the way for the development of novel treatment strategies.
Product Name:
KAT8/MYST1/MOF Rabbit Polyclonal Antibody
SKU:
CAB2208
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KAT8/MYST1/MOF (NP_892003.2).
This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
84148
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KAT8/MYST1/MOF Rabbit pAb (CAB2208) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
