The MYRF Polyclonal Antibody (CAB16355) is a powerful tool for researchers studying the MYRF protein, a transcription factor known for its crucial role in myelination and oligodendrocyte development. This antibody, produced in rabbits, boasts high specificity and sensitivity when detecting MYRF in human samples, making it ideal for use in Western blot applications. By binding to the MYRF protein, researchers can effectively study its function in various cell types, advancing our understanding of its role in neurological disorders and myelin-related diseases.MYRF is a key player in the process of myelination, essential for the proper functioning of the nervous system.
Dysregulation of MYRF has been linked to conditions such as multiple sclerosis, leukodystrophies, and other neurological disorders. By investigating the mechanisms behind MYRF activity, researchers can potentially uncover new therapeutic targets for treating these debilitating diseases.In conclusion, the MYRF Polyclonal Antibody (CAB16355) is a valuable tool for researchers looking to delve deeper into the biological functions of the MYRF protein. With its high specificity and reliability, this antibody is sure to accelerate discoveries in the fields of neurobiology and myelin research.
Product Name:
MYRF Rabbit Polyclonal Antibody
SKU:
CAB16355
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MYRF (NP_001120864.1).
This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
745
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MYRF Rabbit pAb (CAB16355) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
