The MYPN Polyclonal Antibody (CAB16584) is a valuable tool for researchers studying the muscle-specific protein myopalladin (MYPN). This antibody, raised in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. MYPN is a crucial component of the sarcomere, the basic unit of muscle contraction, and is involved in maintaining the structure and function of muscle cells. Dysregulation of MYPN has been implicated in various muscle disorders, making it a promising target for research in the fields of muscle biology and neuromuscular diseases.
By targeting MYPN, researchers can explore its role in muscle development, function, and disease, providing insights that may lead to the development of novel therapies for muscle-related disorders. The MYPN Polyclonal Antibody is a valuable tool for investigating the functions and regulatory mechanisms of MYPN in both normal and pathological conditions.
Product Name:
MYPN Rabbit Polyclonal Antibody
SKU:
CAB16584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MYPN (NP_115967.2).
Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
84665
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using MYPN Rabbit pAb (CAB16584) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
