MYOZ2 Rabbit Polyclonal Antibody (CAB6468)
- SKU:
- CAB6468
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYOZ2 Rabbit Polyclonal Antibody |
SKU: | CAB6468 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human MYOZ2 (NP_057683.1). |
Sequence: | MLSH NTMM KQRK QQAT AIMK EVHG NDVD GMDL GKKV SIPR DIML EELS HLSN RGAR LFKM RQRR SDKY TFEN FQYQ SRAQ INHS IAMQ NGKV DGSN LEGG SQQA PLTP PNTP DPRS PPNP DNIA PGYS GPLK EIPP EKFN TTAV PKYY QSPW EQAI SNDP ELLE ALYP KLFK PEGK AELP DYRS FNRV ATPF GGFE KASR MVKF KVPD FELL LLTD PRFM SFVN PLSG RRSF NRTP KGWI SENI PIVI TTEP TDDT TVPE SEDL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | CS-1; CMH16; C4orf5; FATZ-2; MYOZ2 |
Positive Sample: | Mouse heart,Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Z line, myofibril, sarcomere. |
Calculated MW: | 30kDa |
Observed MW: | 35kDa |
The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
Purification Method: | Affinity purification |
Gene ID: | 51778 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |