MYOT Rabbit Polyclonal Antibody (CAB6439)
- SKU:
- CAB6439
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYOT Rabbit Polyclonal Antibody |
SKU: | CAB6439 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1). |
Sequence: | RPNQ TLPA PKQL RVRP TFSK YLAL NGKG LNVK QAFN PEGE FQRL AAQS GLYE SEEL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100 |
Synonyms: | MFM3; TTID; TTOD; LGMD1; LGMD1A; MYOT |
Positive Sample: | 293T,HepG2,Mouse skeletal muscle,Mouse heart,Rat skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Z line, cytoskeleton, myofibril, sarcolemma, sarcomere. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 9499 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |